PharMab, Inc., located in Zhangjiang HighTech Park of Pudong, Shanghai, China
PharMab positions itself as the leading company in China in developing biopharmaceuticals using genetic engineering techniques. Equipped with the most advanced instruments and laboratory facility, the company has established a unique technology platform stemming from numerous years of experience of its technical team in research and development of biotech products. This technology platform could streamline the production and development of therapeutic monoclonal antibody products and their derivatives.
Biotechnology will become the premier industry in the 21st century. It will be the focal point of global race in technology and economy. The bio-economy, as it builds around the biotech industry, will play the leading role in the growth of global economy in many years to come. The goal of PharMab is to become a leader China in the development of proprietary biotech products using its unique technology platform, and to compete in the international market, as China is elevating its presence and strengthen its competitiveness in the global biotech community.
Technology Platform
1. Antibody Technology Platform
With its unique and powerful techniques in immunization, fusion, and functional screening, PharMab is able to effectively develop monoclonal antibodies with high specificity and affinity against desired disease target molecules. It could subsequently humanize the antibody candidates for therapeutic development.
2. Protein Expression and Purification Platform
With its unique protein expression techniques, PharMab is able to create cell lines derived from mammalian host cells, including Chinese Hamster Ovary (CHO) and murine myeloma cells, to express the target genes at high secretion levels. Paired with its proprietary medium formulation and cell culture techniques, PharMab is also able to grow these cells in suspension culture to produce high levels of protein (including monoclonal antibody) products. In addition, PharMab also has the capability to purify these protein products to high degree of purity using chromatographic methods.
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岗位职责：
1、参与公司在研新药的体内药效学及药代动力学研究（PK）；
2、掌握大小鼠的各种途径给药（皮下，静脉，腹腔），采血（颈筋脉，眼眶，尾静脉）及取材；
3、熟悉肿瘤细胞的培养有良好的无菌操作习惯。
4、熟悉肿瘤药效模型的简历。
5、按要求规范记录实验数据，按时书写实验记录本，管理本部门的一起登记及维护。
6、完成上级交付的其他工作。
岗位要求：
1、动物医学，东吴科学及药学等相关专业本科及以上。
2、勤奋好学，服从工作安排，责任心强。
3、有CRO工作经验者优先。
