PharMab, Inc., located in Zhangjiang HighTech Park of Pudong, Shanghai, China
PharMab positions itself as the leading company in China in developing biopharmaceuticals using genetic engineering techniques. Equipped with the most advanced instruments and laboratory facility, the company has established a unique technology platform stemming from numerous years of experience of its technical team in research and development of biotech products. This technology platform could streamline the production and development of therapeutic monoclonal antibody products and their derivatives.
Biotechnology will become the premier industry in the 21st century. It will be the focal point of global race in technology and economy. The bio-economy, as it builds around the biotech industry, will play the leading role in the growth of global economy in many years to come. The goal of PharMab is to become a leader China in the development of proprietary biotech products using its unique technology platform, and to compete in the international market, as China is elevating its presence and strengthen its competitiveness in the global biotech community.
Technology Platform
1. Antibody Technology Platform
With its unique and powerful techniques in immunization, fusion, and functional screening, PharMab is able to effectively develop monoclonal antibodies with high specificity and affinity against desired disease target molecules. It could subsequently humanize the antibody candidates for therapeutic development.
2. Protein Expression and Purification Platform
With its unique protein expression techniques, PharMab is able to create cell lines derived from mammalian host cells, including Chinese Hamster Ovary (CHO) and murine myeloma cells, to express the target genes at high secretion levels. Paired with its proprietary medium formulation and cell culture techniques, PharMab is also able to grow these cells in suspension culture to produce high levels of protein (including monoclonal antibody) products. In addition, PharMab also has the capability to purify these protein products to high degree of purity using chromatographic methods.
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职位信息
1. 根据工作安排，能够按时按量地完成纯化方案的组织及实施；
2. 主要负责重组蛋白药物的下游纯化小试工艺开发、中试放大及相关技术转移工作；
3. 纯化工艺规程，纯化相关设备的管理维护与SOP等相关文件的撰写
4. 按规范进行实验数据的记录并负责整理汇总，按要求完成纯化相关的技术报告及文件撰写
5. 完成领导安排的其他工作
6. 熟悉蛋白纯化或者有相关课题经验者优先；
岗位要求：
1. 硕士及以上学历，生物技术或相关专业；
2. 良好的英文水平，能查阅英文文献并有一定的英文读写能力；
3. 较强的主动学习能力，具有及时发现问题、并能独立地分析和解决问题的能力；
4. 良好的道德品制，有责任心，工作细致负责，有团队协作精神；
5. 身体健康，符合国家对医药从业人员健康状况相关规定。
